奥替库单抗（INN：Orticumab；开发代号：BI-204、MLDL1278A），或译奥替苏单抗，是一种人单克隆抗体，用作抗炎剂并与oxLDL结合。它充当免疫调节剂。[1]该药物可以用来治疗动脉粥样硬化。[2]该药物由BioInvent公司研究开发。[3]
参考资料[编辑]
- ^ World Health Organization. International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 107 (PDF). WHO Drug Information. 2012, 26 (2).
- ^ Yao Mattisson, Ingrid; Rattik, Sara; Björkbacka, Harry; Ljungcrantz, Irena; Terrinoni, Manuela; Lebens, Michael; Holmgren, Jan; Fredrikson, Gunilla Nordin; Gullstrand, Birgitta; Bengtsson, Anders A.; Nilsson, Jan. Immune responses against oxidized LDL as possible targets for prevention of atherosclerosis in systemic lupus erythematosus. Vascular Pharmacology. 2021-10-01, 140. ISSN 1537-1891. doi:10.1016/j.vph.2021.106863.
- ^ Recruitment of patients completed in phase II study with BI-204. BioInvent. 2012-03-02 [2024-01-21] （英语）.
